Products

Fragile X Diagnostics
Fragile X Syndrome is one of the most commonly inherited diseases caused by CGG trinucleotide repeat expansions in the promoter region of the FMR1 gene on chromosome X. FMR1 alleles are typically categorized into normal, premutation and full mutation alleles based on the number of CGG repeats.
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Fragile X Diagnostics
  • LabChip Dx

      LabChip Dx

      LabChip Dx instrument is designed for molecular diagnostics in clinical research laboraties. The LabChip Dx uses Caliper’s patented microfluidic technology to perform reproducible, high-resolution, electrophoretic separations for analyzing multiplex PCR products for molecular biology applications. The LabChip MultiDX provides a rapid, accurate and cost-effective way of analyzing FragilEaseTM derived PCR products in a high throughput manner. The LabChip MultiDX microfluidics platform is supported by the 5K Chip and 5K Reagents Kit that are designed to provide the user with everything needed to analyze the FragilEase PCR products. This product is CE Marked for IVD use. . . .
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  • FragilEase PCR Assay

      FragilEase PCR Assay

      FragilEase PCR assay is designed to amplify the entire CGG repeat sequence in the FMR1 promoter region. By use of proprietary PCR reagents that allow an accurate amplification of the trinucleotide repeats, FragilEaseTM can reliably detect full mutations with over 900 repeats hence significantly reducing the amount of Southern blot reflexing. In addition, together with the LabChip MultiDX electrophoresis instrument and FraXsoftTM for data analysis and interpretation, we offer a streamlined workflow solution for quick and easy sample analysis with a reporting time of less than a day.

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  • FraXsoft

      FraXsoft

      FraXsoftTM provides an easy-to-use analysis and interpretation option for our FragilEaseTM products. FraXsoftTM allows the analysis of data derived from various microfluidic capillary electrophoresis systems and, based on the number of repeats in user-defined standard samples, calculates the number of CGG trinucleotide repeats in the samples tested. The mutation status of each sample can be classified according to ESHG, ACMG, or user-defined guidelines. FraXsoftTM provides intuitive data visualization for streamlined, quick and clear data interpretation of FragilEaseTM data.

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