Products

Line Immuno Assays
A comprehensive line of Line Immunoassays for various autoimmune disease. Different tests can be applied for screening, confirmatory as well as other applications.
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Line Immuno Assays
  • Arthritis LIA

      Arthritis LIA

      Rheumatoid arthritis (RA) is the most common form of inflammatory joint disease affecting approximately 1 % of the worldwide adult population. Particularly in the early stages the diagnosis of the disease is difficult and efficient diagnostic tools are urgently needed.

      IMTEC-Arthritis-LIA allows the determination of all relevant antibodies and is therefore a powerful tool for the diagnosis of RA.
       
      Assay highlights:
      • Multiplexed assay for diagnosis of Rheumatoid Arthritis
      • Simultaneous detection of multiple autoantibodies for RA and associated disorders
      • Inclusion of RA33 for improved sensitivity of RA
      • Possible to run single test at a time with no special equipment required
      • Inbuilt cutoff control for improved validation
      • CE IVD, CDSCO licensed assay
      Key autoantibodies detected include:
      ACPA (Citrullinated proteins/Anti CCP)
      ACPA antibodies are widely used in clinical practice as part of the ACR criteria (American College of Rheumatology) for RA.
      The use of IMTEC-Arthritis-LIA with four selected CP4 peptides allows a specific ACPA determination.
       
      RF (Rheumatoid factors)
      The major isotype in rheumatoid arthritis is IgM. RF-IgM can be detected in 70-80% of RA patients with established disease and in
      17% of patients with early stage RA.
       
      RA33
      The determination of RA33 specific antibodies increases the diagnostic accuracy and sensitivity of RA diagnosis. RA33 autoantibodies
      are independent from RF and ACPA contribution to the disease. As with ACPA and RF, anti-RA33 antibodies may be present in the
      initial stages of the disease. Additionally, the occurrence of RA33 specific antibodies is correlated to a mild disease progression.
       
      Anti-nuclear antibodies
      RA diagnosis is supported by the ANA parameters dsDNA, SS-A and SS-B for differential diagnoses.
      SS-A antibodies are found in up to 15% of RA patients.
       

       

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  • ANA LIA Maxx

      ANA LIA Maxx

      • ANA Profiling with 17 autoantibodies detected in one strip
      • Special unique antigens - SmD1 and u1snRNP
      • Helps differentiating between SLE, Sjogrens, MCTD, Systemic Sclerosis and Myositis
      • Detects cytoplasmic autoantibodies such as AMA, Ribosomes and Jo-1
      • Addition of Mi-2 and Ku enhance sensitivity for Myositis and Scleroderma
      • Allows reporting of hitherto ANA IF positive ENA negative patient group
      • Inbuilt cutoff control for improved validation
      • No special equipment required
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  • ANA LIA

      ANA LIA

       ANA LIA

      An excellent tool for cost effective ANA profiling with 12 autoantibodies detected on a single strip.

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  • Vasculitis LIA

      Vasculitis LIA

      Simultaneous cost effective determination of PR3, MPO and GBM for diagnosing Vasculitis Autoimmune Disorders and Good Pasture Syndrome.

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  • Liver LIA

      Liver LIA

      Simultaneous cost effective determination of autoantibodies towards LKM, LC1, AMA, Sp100, gp210 and SLA for diagnosing autoimmune liver diseases.

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  • Myositis LIA

      Myositis LIA

      New Improved assay for Myositis includes multiple autoantibodies - Jo1, Mi2, Ku, Pm-Scl, u1snRNP, PL7, PL12

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  • Gastro LIA

      Gastro LIA

      Detection of autoantibodies towards tTG, Gliadin, PCA, Intrinsic Factor and ASCA.

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  • Humascan LIA Software

      Humascan LIA Software

      Automated analysis of Line Immuno-assays (LIA)

      Objective band interpretation, the sensitive system enables objective and reproduceable band interpretation.
      Results in a few seconds, from single test strip to high throughput screening HumaScan takes only seconds for band interpretation.
      Archival storage, archive of total scans, single strips and patient results
       

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